Sarcoid heart disease.

Clinicopathologic correlations. De subitaneis mortibus. XXV. Sarcoid heart disease.

Postmortem findings within the cardiac conduction system are described from the case of a black woman with sarcoid heart disease who died suddenly. Her clinical course had been characterized by recurring ventricular arrhythmias and bouts of syncope. Both the sinus node artery and the atrioventricular (A-V) node artery were sites of focal fibromuscular dysplasia, which thickened slightly the wal...

The two extremes of cardiac sarcoidosis and the effect of Prednisone therapy.

Described herein are clinical and morphologic findings in 2 patients who underwent heart transplantation because of severe heart failure resulting from cardiac sarcoidosis. Although the explanted hearts in each patient had characteristic gross changes of cardiac sarcoidosis, one patient who had been treated with prednisone, had no residual sarcoid granulomas in the myocardium, whereas the other...

Sarcoid heart disease: a review and an appeal.

Chronic cor pulmonale in pulmonary sarcoidosis.

Right-heart overload happens relatively rarely in sarcoidosis, even with fibroemphysematous changes. Of 21 cases that we studied, six (28%) had clinical and/or electrocardiographic features of cor pulmonale. The cause of cor pulmonale often evoked is an invasion of the walls of pulmonary vessels by sarcoid granulomas or their compression by the fibrotic process. Pathological studies in one pati...

Polymorphic cutaneous sarcoidosis: A case report

Sarcoidosis (Besnier-Boeck-Schaumann disease) is a multisystem disease of unknown etiology with various cutaneous presentations. It is characterized by the presence of non-caseating ‘naked’ granulomas in the affected tissue. We report a case of polymorphic cutaneous sarcoid in a 39-year-old immunocompetent male. He was visited at our outpatient department with multiple asymptomatic red colored ...

Sarcoid in cancer patients: clinical characteristics and associated disease status.

BACKGROUND The increased risk of cancer in patients with sarcoidosis is well established, but there is little information regarding sarcoid diagnosed during or following cancer. The purpose of this study is to describe and analyze the disease status and events associated with the diagnosis of sarcoid in cancer patients. METHODS At a large cancer center, we identified 64 patients with a pathol...